Despite the potential of long duration earthquakes in subduction zones, little attention has been paid on seismic vulnerability assessment of highway bridges that are simultaneously undergoing prolonged corrosion deterioration. Consequently, this study presents a framework for considering the joint impact of ground motion duration and chloride-induced corrosion deterioration on the lifetime seismic vulnerability of aging highway bridge structures. The proposed framework is then applied to a representative case-study multi-span simply supported highway bridge located in subduction earthquake zone within Seattle, U.S.A. A detailed three-dimensional analytical models are first developed that account for the nonlinear behaviour of different bridge components, including experimentally validated column model capable of capturing cyclic degradation of force–deformation response. Suites of spectrally equivalent